Abnormalities in Hemispheric Specialization of Caudate Nucleus Connectivity in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia.
IMPORTANCE Hemispheric specialization of the human brain is a marker of successful neurodevelopment. Altered brain asymmetry that has been repeatedly reported in schizophrenia may represent consequences of disrupted neurodevelopment in the disorder. However, a complete picture of functional specialization in the schizophrenic brain and its connectional substrates is yet to be unveiled. OBJECT...
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BACKGROUND Previously, we reported abnormal volume and global shape in the caudate nucleus in schizotypal personality disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures. METHODS Thirty-two female and 15 male SPDs, and 29 female and 14 male normal controls (NCLs), underwen...
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Traditionally, anatomical and physiological descriptions of hemispheric specialization have focused on hemispheric asymmetries of local brain structure or local functional properties, respectively. This article reviews the current state of an alternative approach that aims at unraveling the causes and functional principles of hemispheric specialization in terms of asymmetries in connectivity. S...
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ژورنال
عنوان ژورنال: JAMA Psychiatry
سال: 2015
ISSN: 2168-622X
DOI: 10.1001/jamapsychiatry.2014.3176